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1

Impact of exposure duration by low molecular weight compounds on interferon-γ and interleukin-4 mRNA expression and production in the draining lymph nodes of mice

Rob J Vandebriel, Wim H De Jong, Jerome J.A Hendriks, Henk Van Loveren

Journal:

Year:

2003

Language:

english

File:

PDF, 339 KB

english, 2003

2

Distribution, Elimination, and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-Day Oral Exposure

van der Zande, Meike, Vandebriel, Rob J., Van Doren, Elke, Kramer, Evelien, Herrera Rivera, Zahira, Serrano-Rojero, Cecilia S., Gremmer, Eric R., Mast, Jan, Peters, Ruud J. B., Hollman, Peter C. H., H

Journal:

Year:

2012

Language:

english

File:

PDF, 3.80 MB

english, 2012

3

Differences in the Induction of Macrophage Cytotoxicity by the Specific T Lymphocyte Factor, Specific Macrophage Arming Factor (SMAF), and the Lymphokine, Macrophage Arming Factor (SMAF), and the Lymphokine, Macrophage Activating Factor (MAF)

De Groot, Jan W., De Weger, Roelof A., Vandebriel, Rob J., Den Otter, Willem

Journal:

Year:

1989

Language:

english

File:

PDF, 1.52 MB

english, 1989

4

The effect of zirconium doping of cerium dioxide nanoparticles on pulmonary and cardiovascular toxicity and biodistribution in mice after inhalation

Dekkers, Susan, Miller, Mark R., Schins, Roel P.F., Römer, Isabella, Russ, Mike, Vandebriel, Rob J., Lynch, Iseult, Belinga-Desaunay, Marie-France, Valsami-Jones, Eugenia, Connell, Shea P., Smith, Ian

Journal:

Year:

2017

Language:

english

File:

PDF, 1.80 MB

english, 2017

5

Immunotoxicology: A brief history, current status and strategies for future immunotoxicity assessment

Germolec, Dori, Luebke, Robert, Rooney, Andrew, Shipkowski, Kelly, Vandebriel, Rob, van Loveren, Henk

Journal:

Current Opinion in Toxicology

Year:

2017

Language:

english

File:

PDF, 306 KB

english, 2017

6

The crystal structure of titanium dioxide nanoparticles influences immune activity in vitro and in vivo

Vandebriel, Rob J., Vermeulen, Jolanda P., van Engelen, Laurens B., de Jong, Britt, Verhagen, Lisa M., de la Fonteyne-Blankestijn, Liset J., Hoonakker, Marieke E., de Jong, Wim H.

Journal:

Particle and Fibre Toxicology

Year:

2018

Language:

english

File:

PDF, 816 KB

english, 2018

7

Mechanism of Action of TiO 2 : Recommendations to Reduce Uncertainties Related to Carcinogenic Potential

Braakhuis, Hedwig M., Gosens, Ilse, Heringa, Minne B., Oomen, Agnes G., Vandebriel, Rob J., Groenewold, Monique, Cassee, Flemming R.

Journal:

Annual Review of Pharmacology

Year:

2021

File:

PDF, 576 KB

2021

8

Consequences of the expression of lipopolysaccharide-modifying enzymes for the efficacy and reactogenicity of whole-cell pertussis vaccines

Jeroen Geurtsen, Rob J. Vandebriel, Eric R. Gremmer, Betsy Kuipers, Jan Tommassen, Peter van der Ley

Journal:

Microbes and Infection

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

9

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: First round

G. Ehling, M. Hecht, A. Heusener, J. Huesler, A.O. Gamer, H. van Loveren, Th. Maurer, K. Riecke, L. Ullmann, P. Ulrich, R. Vandebriel, H.-W. Vohr

Journal:

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

10

Detection of allergic properties of components from latex gloves by the auricular lymph node assay (ALNA) in the mouse

W.H. De Jong, H. Van Der Vliet, M. Tentij, R. Legtenberg, R. Vandebriel, H. Van Loveren

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 184 KB

english, 1997

11

Quantification of in vitro tributyltin oxide exposure effects on lymphocyte proliferation in rat splenocytes and human PBMC aimed at calculating inter- and intraspecies variation factors for risk assessment

R.J. Vandebriel, J. Garssen, B.N. Hudspith, W. Slob, C. Meredith, H. van Loveren

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 188 KB

english, 1997

12

A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins

François M.M van Och, Wout Slob, Wim H de Jong, Rob J Vandebriel, Henk van Loveren

Journal:

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

13

Comparison of dose–responses of contact allergens using the guinea pig maximization test and the local lymph node assay

François M.M. van Och, Rob J. Vandebriel, Menk K. Prinsen, Wim H. De Jong, Wout Slob, Henk van Loveren

Journal:

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

14

Erratum to “Comparison of dose–responses of contact allergens using the guinea pig maximization test and the local lymph node assay”: [Toxicology 167 (2001) 207–215]

François M.M van Och, Rob J Vandebriel, Menk K Prinsen, Wim H De Jong, Wout Slob, Henk van Loveren

Journal:

Year:

2002

File:

PDF, 56 KB

2002

15

Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses

Wim H De Jong, Marlies Tentij, Sander W Spiekstra, Rob J Vandebriel, Henk Van Loveren

Journal:

Year:

2002

Language:

english

File:

PDF, 304 KB

english, 2002

16

Effect of prolonged exposure to low antigen concentration for sensitization

François M.M van Och, Rob J Vandebriel, Wim H De Jong, Henk van Loveren

Journal:

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

17

Altered cytokine (receptor) mRNA expression as a tool in immunotoxicology

Rob J Vandebriel, Henk Van Loveren, Clive Meredith

Journal:

Year:

1998

Language:

english

File:

PDF, 164 KB

english, 1998

18

In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes

Rob J. Vandebriel, Sander W. Spiekstra, Barry N. Hudspith, Clive Meredith, Henk Van Loveren

Journal:

Year:

1999

Language:

english

File:

PDF, 549 KB

english, 1999

19

Environmental and lifestyle factors may act in concert to increase the prevalence of respiratory allergy including asthma

Steerenberg, Van Amsterdam, Vandebriel, Vos, Van Bree, Van Loveren

Journal:

Clinical & Experimental Allergy

Year:

1999

Language:

english

File:

PDF, 87 KB

english, 1999

20

UVB exposure-induced systemic modulation of Th1- and Th2-mediated immune responses

Garssen, Vandebriel, De Gruijl, Wolvers, Van Dijk, Fluitman, Van Loveren

Journal:

Year:

1999

Language:

english

File:

PDF, 132 KB

english, 1999

21

Interleukin-10 is an Unequivocal Th2 Parameter in the Rat, whereas Interleukin-4 is Not

R. J. Vandebriel, C. Meredith, M. P. Scott, M. Van Dijk, H. Van Loveren

Journal:

Scandinavian Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 220 KB

english, 2000

22

Evaluation of the Rapid Scale-up of Collaborative TB/HIV Activities in TB Facilities in Rwanda, 2005-2009

Eric S Pevzner, Greet Vandebriel, David W Lowrance, Michel Gasana, Alyssa Finlay

Journal:

BMC Public Health

Year:

2011

Language:

english

File:

PDF, 221 KB

english, 2011

23

Initial immunochemical characterization of specific macrophage-arming factor

Roel A. De Weger, Rob J. Vandebriel, Hans Slager, Dennis Mans, Henk Van Loveren, Bert Wilbrink, Hub F. J. Dullens, Willem Den Otter

Journal:

Cancer Immunology, Immunotherapy

Year:

1989

Language:

english

File:

PDF, 953 KB

english, 1989

24

Production of specific macrophage-arming factor precedes cytotoxic T lymphocyte activity in vivo during tumor rejection

Hub F. J. Dullens, Roel A. De Weger, Martin Van Der Maas, Piet J. Den Besten, Rob J Vandebriel, Willem Den Otter

Journal:

Cancer Immunology, Immunotherapy

Year:

1989

Language:

english

File:

PDF, 826 KB

english, 1989

25

Gene polymorphisms within the immune system that may underlie drug allergy

RobJ. Vandebriel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2004

Language:

english

File:

PDF, 186 KB

english, 2004

26

Lung response toBordetella pertussisinfection in mice identified by gene-expression profiling

Sander Banus, Jeroen Pennings, Rob Vandebriel, Piet Wester, Timo Breit, Frits Mooi, Barbara Hoebee, Tjeerd Kimman

Journal:

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

27

An Efficient Memory Organization for High-ILP Inner Modem Baseband SDR Processors

Bjorn De Sutter, Osman Allam, Praveen Raghavan, Roeland Vandebriel, Hans Cappelle, Tom Vander Aa, Bingfeng Mei

Journal:

Journal of Signal Processing Systems

Year:

2010

Language:

english

File:

PDF, 1.91 MB

english, 2010

28

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round

G. Ehling, M. Hecht, A. Heusener, J. Huesler, A.O. Gamer, H. van Loveren, Th. Maurer, K. Riecke, L. Ullmann, P. Ulrich, R. Vandebriel, H.-W. Vohr

Journal:

Year:

2005

Language:

english

File:

PDF, 112 KB

english, 2005

29

Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1α and IL-18 production by a murine and human keratinocyte cell line

François M.M. Van Och, Henk Van Loveren, Josien C. Van Wolfswinkel, Anja J.C. Machielsen, Rob J. Vandebriel

Journal:

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

30

Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users

Hilda J. I. de Jong, Rob J. Vandebriel, Siti R. F. Saldi, Liset van Dijk, Henk van Loveren, Jan Willem Cohen Tervaert, Olaf H. Klungel

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2012

Language:

english

File:

PDF, 123 KB

english, 2012

31

Specific T-Cell Factors That Initiate Cellular Immune Responses Are Produced by CD4-, CD8-, Vβ8- Lymphocytes and Are Present in Nude Mice

Rob J. Vandebriel, Roel A. de Weger, Henk Van Loveren, Johan Garssen, Mireille N.M. Van Poppel, Dick F. Van Wichen, Willem Den Otter

Journal:

Cellular Immunology

Year:

1994

File:

PDF, 543 KB

1994

32

Effects ofin VivoExposure to Bis(tri-n-butyltin)oxide, Hexachlorobenzene, and Benzo(a)pyrene on Cytokine (Receptor) mRNA Levels in Cultured Rat Splenocytes and on IL-2 Receptor Protein Levels

Rob J. Vandebriel, Clive Meredith, Mary P. Scott, Paul J.M. Roholl, Henk Van Loveren

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 1.55 MB

english, 1998

33

Assessment of Preferential T-Helper 1 or T-Helper 2 Induction by Low Molecular Weight Compounds Using the Local Lymph Node Assay in Conjunction with RT-PCR and ELISA for Interferon-γ and Interleukin-4

Rob J. Vandebriel, Wim H. De Jong, Sander W. Spiekstra, Mariska Van Dijk, Angelique Fluitman, Johan Garssen, Henk Van Loveren

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

34

Cytokine Production Induced by Low-Molecular-Weight Chemicals as a Function of the Stimulation Index in a Modified Local Lymph Node Assay: An Approach to Discriminate Contact Sensitizers from Respiratory Sensitizers

François M.M. Van Och, Henk Van Loveren, Wim H. De Jong, Rob J. Vandebriel

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

35

Specific T-cell factor production and lymphocytes in the direct surroundings of a subcutaneous allogeneic tumor

Rob J. Vandebriel, Dick F. Van Wichen, Mireille N.M. Van Poppel, Margee Robertus-Teunissen, Detlef Zimmermann, Hendrik C. Korswagen, Nancy E.M. Van Emmerik, Roel A. De Weger

Journal:

Cellular Immunology

Year:

1992

Language:

english

File:

PDF, 5.67 MB

english, 1992

36

Association Between Statin Use and Lupus-Like Syndrome Using Spontaneous Reports

Hilda J.I. de Jong, Jan Willem Cohen Tervaert, Siti R.F. Saldi, Rob J. Vandebriel, Patrick C. Souverein, Ronald H.B. Meyboom, Henk van Loveren, Olaf H. Klungel

Journal:

Seminars in Arthritis and Rheumatism

Year:

2011

Language:

english

File:

PDF, 254 KB

english, 2011

37

In vitro assessment of sensitizing activity of low molecular weight compounds

Rob J. Vandebriel, François M.M. Van Och, Henk van Loveren

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

38

Strategies for the optimisation of in vivo experiments in accordance with the 3Rs philosophy

Judith C. Madden, Mark Hewitt, Katarzyna Przybylak, Rob J. Vandebriel, Aldert H. Piersma, Mark T.D. Cronin

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 410 KB

english, 2012

39

The role of Toll-like receptor-4 in pertussis vaccine-induced immunity

Sander Banus, Rachel M Stenger, Eric R Gremmer, Jan AMA Dormans, Frits R Mooi, Tjeerd G Kimman, Rob J Vandebriel

Journal:

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

40

Comparative gene expression profiling in two congenic mouse strains followingBordetella pertussisinfection

Sander Banus, Rob J Vandebriel, Jeroen LA Pennings, Eric R Gremmer, Piet W Wester, Henk J van Kranen, Timo M Breit, Peter Demant, Frits R Mooi, Barbara Hoebee, Tjeerd G Kimman

Journal:

BMC Microbiology

Year:

2007

Language:

english

File:

PDF, 793 KB

english, 2007

41

a proteinaceous particle from the wax moth, Galleria mellonella

R.J. Vandebriel, N.F. Moore

Journal:

Journal of Invertebrate Pathology

Year:

1985

Language:

english

File:

PDF, 753 KB

english, 1985

42

Respiratory sensitization: Advances in assessing the risk of respiratory inflammation and irritation

Rob Vandebriel, Conchita Callant Cransveld, Daan Crommelin, Zuzana Diamant, Berend Glazenburg, Guy Joos, Frieke Kuper, Andreas Natsch, Frans Nijkamp, Hub Noteborn, Raymond Pieters, David Roberts, Erwi

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 230 KB

english, 2011

43

Prevalidation of a human T cell proliferation assay to identify immunosuppressive compounds

J.P. Ten Klooster, M. Teunis, A. Kleensang, C. Krul, H. Van Loveren, E. Corsini, R. Vandebriel, R. Pieters

Journal:

Toxicology Letters

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

44

Lung pathology and immediate hypersensitivity in a mouse model after vaccination with pertussis vaccines and challenge with Bordetella pertussis

Rob J. Vandebriel, Eric R. Gremmer, Jolanda P. Vermeulen, Sandra M.M. Hellwig, Jan A.M.A. Dormans, Paul J.M. Roholl, Frits R. Mooi

Journal:

Year:

2007

Language:

english

File:

PDF, 947 KB

english, 2007

45

Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: Modification of vaccine-induced immune responses

Jeroen Geurtsen, Floris Fransen, Rob J. Vandebriel, Eric R. Gremmer, Liset J.J. de la Fonteyne-Blankestijn, Betsy Kuipers, Jan Tommassen, Peter van der Ley

Journal:

Year:

2008

Language:

english

File:

PDF, 449 KB

english, 2008

46

Response of MUTZ-3 dendritic cells to the different components of the Haemophilus influenzae type B conjugate vaccine: Towards an in vitro assay for vaccine immunogenicity

Marcel H.N. Hoefnagel, Jolanda P. Vermeulen, Rik J. Scheper, Rob J. Vandebriel

Journal:

Year:

2011

Language:

english

File:

PDF, 722 KB

english, 2011

47

Toxicogenomics in the assessment of immunotoxicity

Kirsten A. Baken, Rob J. Vandebriel, Jeroen L.A. Pennings, Jos C. Kleinjans, Henk van Loveren

Journal:

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

48

Association of Bordetella pertussis with host immune cells in the mouse lung

Rob J. Vandebriel, Sandra M.M. Hellwig, Jolanda P. Vermeulen, Jan H.G. Hoekman, Jan A.M.A. Dormans, Paul J.M. Roholl, Frits R. Mooi

Journal:

Microbial Pathogenesis

Year:

2003

Language:

english

File:

PDF, 562 KB

english, 2003

49

In vitro immunotoxicity of bis(tri-n-butyltin)oxide (TBTO) studied by toxicogenomics

Kirsten A. Baken, Joanna Arkusz, Jeroen L.A. Pennings, Rob J. Vandebriel, Henk van Loveren

Journal:

Year:

2007

Language:

english

File:

PDF, 556 KB

english, 2007

50

Effect of exposure in vivo to tributyltin oxide (TBTO) and ozone on cytokine mRNA levels

R.J. Vandebriel, M.P. Scott, J.A.H. Wijnands, L. Van Bree, C. Meredith, H. van Loveren

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 143 KB

english, 1995

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